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case study

Repositioning an HIV therapy in a category dominated by alternatives

Client
Merck Delstrigo (via CloudRaker)
Role
Senior Copywriter & Content Strategist
Channel
brandlong-form

Results

  • Category repositioning — NNRTIs reframed as a viable switch in a PI/INI-dominated market
  • HCP switch-conversation tools — frameworks for the talk with stable-regimen patients
  • Patient profile development surfacing the real-world candidate set for NNRTI switch
  • Doravirine safety/tolerability copy built for HCP-direct use, not slide-deck-only

The brief

HIV treatment had settled into a pattern: PIs and INIs were standard of care, NNRTIs were largely off the consideration list. Delstrigo (doravirine) needed a brand story that didn’t just inform HCPs of an option but actively reframed when an NNRTI made sense in the first place — without contradicting the prevailing treatment paradigm.

What I led

  • Safety profile messaging on doravirine, emphasizing tolerability in language HCPs could use directly with patients
  • Patient profiles illustrating who, exactly, was suitable for switching to NNRTI-based therapy — real-world examples grounded in clinical practice
  • Brand repositioning copy that surfaced NNRTIs as a viable switch option rather than positioning Delstrigo against PIs/INIs directly
  • Switch-conversation tools for HCPs — frameworks for raising the conversation with patients on stable regimens

Why it matters

This is the case study for any brand needing to reframe how its category is considered — not louder messaging in the existing frame, but a new frame that gives the audience a fresh reason to look. The strategic discipline transfers to any brand fighting category gravity.


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